Bioavailability will be affected by the method you use to ingest the CBD and if the CBD is an isolate, broad spectrum or full spectrum
extract. (Full spectrum will provide the most nutrients and beneficial cofactors
.) Of the five common ways to consume CBD--vaping, transdermal patches, topical creams, edibles, and CBD oils
--each method interacts differently with your body, takes varying times to penetrate and remain active in your circulatory system.
How you ingest anything matters and this holds true for CBD as well. While vaping delivers the most amount of CBD, it can detrimentally affect your lungs, creates second-hand smoke and is not very discreet. Edibles, tinctures and oils are all affected by our metabolism through the “first-pass effect”.